Buzzer Round for NCLEX…

Today I am introducing a brand new area which will help you in your studies for nursing competitive exams. I like to call it as the BUZZER ROUND FOR NCLEX…

Continue reading Buzzer Round for NCLEX…

TAMIFLU

The year 2018 is more of a bitter one except for one or two sweet memories. After the devastating flood, which drained me out physically and mentally, it’s the turn of H1N1 flu to attack my health.

Continue reading TAMIFLU

HOW GOOD ARE YOU AT MED SURG?

Thought to share some reminders in med surg, which are very minor but much useful information. A free printable of the Q card is there at the end of this topic,  with answers. Continue reading HOW GOOD ARE YOU AT MED SURG?

ACCEPTING THE UNAVOIDABLE… MY PERSONAL EXPERIENCES DURING KERALA FLOOD 2018

Let me say SORRY to all my dear readers…This very gap in my posts was really unexpected. Firstly, even though in vacation my plans to continue to write was a big fail, as we were stuck in the Flood that hit my homeland…our gods own country…Kerala.

Kerala is a calm and serene destination in south India. We the people of Kerala are always blessed with the finest climates, and the rainy season – the monsoon- on which agricultural Kerala relays on, is a time of blend emotions, that Keralites always cherish. The school reopenings, all the busy rainy mornings, playful kids at the roadside puddles, that patting sounds of rain at the window sills…

But, the rainy season of 2018, was not like the previous years. It was as if GOD had plans, not a single, but many many plans to each individual Keralites…and that’s why each one of us have our own stories to share, stories of horror, and sleepless nights, prayers and religious harmony, cooperation and compassion, moreover the stories of acceptance of the unavoidable, acceptance of the supernatural power above .

Here is the front view of my house during the flood. A picture captured by my relative who took shelter on the first floor of our house. Later they were rescued by the helicopter rescue team.

My House

The aftermath of the devastating flood…

This slideshow requires JavaScript.

 

Days of cleaning and chlorination followed and still some more electrical and plumbing works pending.

All those flood days taught many valuable lessons.

Firstly, only a neighbor worth more than a distant relative.

Then, we understood the warmth of family bonds, as many of us took shelter in those relatives house, we haven’t been in touch for long.

We came to understand, how to live with minimal resources.

We learned to be in harmony irrespective of religion, financial or social status.

Now, after three months, our Kerala is almost back on track. And once again is open to the world with her natural beauty…..

Bonus: You could watch a documentary on 12th Nov 2018 on Discovery Channel at  9 pm (IST ) ‘KERALA FLOODS – THE HUMAN STORY’

ANTIANGINALS

 

A case of chest pain in the emergency department always go for the protocol of angina and/or MI. The MI protocol primarily focuses on relief of pain with antianginal medications.

What are Antianginal Medications?

Those medicines which reduce the oxygen demand of the myocardium or increases the oxygen supply to the heart are known as The Antianginal Drugs.

Examples

Here I will discuss the details of Nitrates

NITRATES

Classification

Screenshot_20180720-091006_1.jpg

Indications of NITRATES

  • Acute Angina – Prophylaxis and Treatment
  • Chronic Angina treatment
  • Hypertension associated with MI or CHF
  • Raynaud’s disease (NTG ointment)

Mechanism of Action

Antianginals mainly work either by decreasing the Oxygen demand or by increasing oxygen supply.

PHARMACOKINETICS

  • ONSET – 2min (S/L); 3min (PO); 30min (Topical)
  • HALF LIFE – 5-7min
  • METABOLISM – In Liver

Contraindications

  • Sensitivity to Nitrates
  • Severe Anemia
  • Hepatic or Renal dysfunction
  • Hypotension
  • Head Trauma
  • Cerebral Haemorrhage

Side Effects

  • Dizziness (especially at the beginning of the treatment)
  • Orthostatic Hypotension
  • Topical application may lead to dermatitis
  • A throbbing Headache
  • Flushing of face
  • Reflex tachycardia

Drug Interaction

Additive hypotension with other ANTIHYPERTENSIVES

SILDENAFIL (Viagra) can cause additive hypotension

Intake of ALCOHOL along with NTG also cause hypotension

NURSING CONSIDERATIONS WHILE ADMINISTERING NITRATES

About the nurse’s responsibility, there is a lot to discusses. So I am dealing with it as a separate post. You can read it  NURSING CONSIDERATIONS WHILE ADMINISTERING NITRATES

Are you administering Inj Clexane safely?

 

On physical examination of a newly admitted case of bedridden elderly patient I noticed circular red patches around 3-4 cm radius over right and left lateral thighs. I  recognised it as the local damage due to the improper administration of Injection Clexane, a subcutaneously administered antithrombotic, which is a Low Molecular Weight Heparin. This led me to the thought,” How can we administer inj clexane properly?”. ” How safely we are administering it daily?”. In this post, I will share my knowledge about inj Clexane and the recommendations for its safe administration.

WHAT IS INJ CLEXANE?

It is an Antithrombotic.

The active ingredient of Inj Clexane is Enoxaparin Sodium. It is a low molecular weight heparin (LMWH).

LMWH is produced by chemically splitting heparin into one-third of its original size. Has fewer side effects than heparin and has more predictable anticoagulant action. 

THERAPEUTIC INDICATIONS

  • Prophylaxis of Venous thromboembolic diseases in Surgical patients(orthopaedic and general surgeries) and in Medical patients(rheumatic disease)
  • Treatment of DVT and Pulmonary Embolism (PE)
  • Acute STEMI
  • Unstable Angina and NSTEMI
  • In Haemodialysis – To prevent thrombus formation in Extracorporeal Circulation

CONTRAINDICATIONS

  • Active significant bleeding
  • Hypersensitivity
  • Thrombocytopenia
  • Vascular aneurysms
  • Oesophageal varices
  • Hyperkalemia

SIDE EFFECTS

  • Haemorrhage
  • Haematoma
  • Anaemia
  • Ecchymosis
  • Confusion
  • Diarrhoea
  • Haematuria

DRUG INTERACTIONS

  • Aspirin
  • NSAIDs
  • Dextran
  • Warfarin

Interaction with these drugs increase the risk of bleeding

NURSING CONSIDERATIONS

METHODS OF ADMINISTRATION

Should NOT BE  administered by IM route. IM CAUSES HAEMATOMA.

Preferred injection method is subcutaneous

In special cases, IV routes are used

Screenshot_20180715-095804_1.jpg

TECHNIQUE FOR SAFE S/C ADMINISTRATION

  • Patient must be preferably in a lying position.
  • DO NOT expel the air bubble from the syringe. {This is to avoid the loss of drug while using prefilled syringes}
  • PREFERRED SITE: The subcutaneous tissue of the anterolateral or posterolateral ABDOMINAL WALL
  • It is administered as a DEEP S/C INJECTION
  • The whole length of the needle should be introduced PERPENDICULARLY, not from sides, into the skinfold gently held between the thumb and the index finger. SKINFOLD SHOULD BE HELD THROUGHOUT THE INJECTIONInjection_subcutaneous_insulinsyringe_angle_EQUIP_ILL_EN

 

  • DO NOT rub the injection site after administration

IV BOLUS ADMINISTRATION (Only for Acute STEMI)

  • Initiate the treatment with single dose IV bolus injection, followed by  s/c injection
  • For IV, Multidose Vials or Prefilled syringes can be used

حقن-كليكسان-CLEXANE

 

clexane multidose vial

 

  • IV administration should not be mixed or coadministered  with any other medications
  • Safely administered with NS (normal saline .9%) solution or 5%D in water.

MONITORING AND SAFETY IMPLICATIONS

  • Lab monitorings include

Baseline coagulation studies: aPTT, PT, INR, clotting time

periodic CBC for blood counts

periodic urine and stool examination for occult blood

  • apply direct pressure for venipuncture site for long durations
  • Assess for any history of allergy for the patient
  • Monitor for any signs of side effects

PATIENT TEACHING

  • Educate regarding the increased risk of bleeding while taking inj clexane, monitoring for bleeding and management of bleeding
  • Instruct not to take any OTC medications without the consultation of the doctor
  • Patients who will self-administer it must be instructed on correct s/c administration technique
  • Instruct not to breastfeed while taking inj clexane

Let us join hands for safe administration of antithrombotics, to ensure the full benefit of the therapy with minimal potential harm.

 

 

 

 

NURSING CONSIDERATIONS WHILE ADMINISTERING NITRATES

while discussing the antianginal drugs, especially Nitrates I found there is a lot to tell you. Mainly, on the precautions that you must take while administering IV nitroglycerine. So I thought to write a separate post on the nursing considerations. I believe this would be useful for you throughout your nursing career and while preparing for any international nursing licence exams.

I arranged the points under two headings. First,  points to remember on administering all preparations other than IV and  Second,  points to remember on administering IV Nitroglycerine.

ADMINISTRATION OF NITRATES

74108550-heart-glass-of-water-and-blister-packs-of-pills

Oral Sustained-Release Tablets of NTG should be taken on an empty stomach with full glass of water

GTN tablet

Carry S/L tablets in the glass bottle, tightly capped. Nitroglycerin can lose potency if exposed to light, moisture, or heat. Also to discard the tablets and get a new supply every 8 weeks. Now, NTG sprays are prefered over the tablets due to the longer shelf life when compared to its S/L form.

Cartoon Ambulance Car Stock Animation | 10496218 for Ambulance Animation

If the chest pain is not relieved by 1 S/L tab, give 2 more tabs with a 5-minute interval. even after the third tablet (within 15 minutes), the pain persists, shift the client to the emergency department as the chest pain can be an MI and not Angina. your chest pain… is it simply a chest pain or a heart attack???

tablet intake sitting position

S/L tabs or sprays to be taken in sitting position to avoid postural hypotension

 

Screenshot_20180621-153501_1.jpg

Explain that slight stinging, burning, or tingling under the tongue indicates the potency of the drug. Get a new supply if these sensations are not present.

avoid alcoho

Avoid alcohol, hot baths, saunas, and whirlpools, as they can cause vasodilatation and lead to hypotension and fainting.

Screenshot_20180621-163745_1.jpg

To minimise the tolerance to NTG the patches are removed after 12 hours. And a 12-hour gap is given before the next patch

  •  Instruct client to not take sildenafil (Viagra) within 24 hours after taking
    nitrates, and wait 24 hours after taking Viagra to resume nitrate therapy

IV ADMINISTRATION OF NITRATES

nitroglycerin-iv-bottle-held-nurse-tubing-81393538

Use glass containers and tubings or PVC tubings to administer IV GTN. (other materials absorb it and reduce potency)

syringe n infusion pump

Administer  using an infusion pump that can maintain constant infusion rate

Printable-Blood-Pressure-Chart-Template

Strictly maintain BP CHART. Monitor the BP every 5 -15 minutes

NTG patch

Remove topical forms when starting IV infusion

  • Administer nitroglycerine diluted in 5% dextrose. Do not mix it with any other drugs
  • Nitrates can develop a tolerance to the drug. May need 10-12 hr/day nitrate-free interval to avoid tolerance development
  • Sudden cessation of the therapy may cause withdrawal reactions. Gradually reduce the dose and withdraw the therapy.
  • Intravenous Drip:  Begin at 5 mcg/min and titrate every 3-5 minutes to therapeutic response and stable vital signs. Titrate NTG infusion until relief of chest pain or a maximum of 200 mcg/min dose is achieved.